Compound ID | 409

LY228238

Class: Beta-lactam (cephalosporin, carbacephem [loracarbef derivative])

Spectrum of activity: Gram-positive  &  Gram-negative
Description: KASHER, J. S.; J. A. EUDALY, R. JOHNSON & J. SHOUFLER: Pharmacokinetics of orally absorbed beta-lactam antibiotics LY228238 and LY257128 in laboratory animals. Program and Abstracts of the 28th Intersci. Conf. on Antimicrob. Agents Chemother., No. 535, p. 202, Los Angeles, Oct. 23-26, 1988
Institute where first reported: Eli Lilly, USA
Year first mentioned: 1988
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: Low oral bioactivity in monkeys compared with rats and mice

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