Compound ID | 414

Update compound information

ER-35786

Synonym(s): E1010

Class: Beta-lactam

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Cell wall synthesis inhibitor
Target Pathogen: Active against Pseudomonas sp.
Description: Semisynthetic compound; carbapenem-type
Institute where first reported: Eisai Co Ltd
Year first mentioned: 1995
Highest development stage: Phase 1
Development status: Inactive
Chemical structure(s):
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Molecular weight: 447.98
Iso. SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)[C@@H]([C@@H]4CCNC4)O)C(=O)O)[C@@H](C)O.Cl
InChI Key: WRVJTXDJDKITNK-XNGFCKKMSA-N
Can. SMILES: C[C@@H]1[C@@H]2[C@@H]([C@@H](C)O)C(=O)N2C(=C1S[C@H]3C[C@@H]([C@@H]([C@@H]4CCNC4)O)NC3)C(=O)O.Cl
InChI: InChI=1S/C19H29N3O5S.ClH/c1-8-14-13(9(2)23)18(25)22(14)15(19(26)27)17(8)28-11-5-12(21-7-11)16(24)10-3-4-20-6-10;/h8-14,16,20-21,23-24H,3-7H2,1-2H3,(H,26,27);1H/t8-,9-,10-,11+,12+,13-,14-,16-;/m1./s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6918311
Guide to Pharmacology: E-1010 free base
Citation: https://journals.asm.org/doi/10.1128/aac.41.2.298

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