Compound ID | 425

FK041

Class: Beta-lactam (cephalosporin)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: FK041 demonstrated similar activity to cefdinir against MSSA, S. pneumoniae, B. catarrhalis, H. influenzae, E. coli, K. pneumoniae and P. mirabilis.
Description: Hatano K, Kawabata K, Yamamoto H, et al. FK041, a new orally active Cephalosporin: In vitro and in vivo antibacterial activity. 36th-Intersci-Conf-Antimicrobial-Agents-Chemother 1996; 122.
Institute where first reported: Fujisawa Pharm. Co., Japan
Year first mentioned: 1996
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 481.53
Iso. SMILES: C1C(=C(N2C(S1)C(C2=O)NC(=O)C(=NO)C3=CSC(=N3)N)C(=O)O)SCC4=CNN=C4
InChI Key: RNWMKMFWVBYAMX-UHFFFAOYSA-N
Can. SMILES: C1=C(C=NN1)CSC2=C(C(=O)O)N3C(=O)C(C3SC2)NC(=O)C(=NO)C4=CSC(=N4)N
InChI: InChI=1S/C16H15N7O5S3/c17-16-20-7(4-31-16)9(22-28)12(24)21-10-13(25)23-11(15(26)27)8(5-30-14(10)23)29-3-6-1-18-19-2-6/h1-2,4,10,14,28H,3,5H2,(H2,17,20)(H,18,19)(H,21,24)(H,26,27)

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