Compound ID | 432
ME1209
Synonym(s): CP-6679
Class: Beta-lactam (cephalosporin)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Similar activity to ceftazidime, cefeprime, and cefozopran against a clinical isolate of MRSA but against ceftazidime resistant mutant or aztreonam- resistant MRSA, ME1209 had lower MICs by at least 4 fold. |
| Propensity to select resistant mutants: | Lower propensity to select for resistant strains than ceftazidime |
| Description: | Yoshida T, Ida I, Kurazono M, et al. ME1209 (CP6679), a new parenteral Cephalosporin II. In vitro and in vivo activity against Pseudomonas aeruginosa. 38th Intersci Conf Antimicrob Agents Chemother. 1998. |
| Institute where first reported: | Meiji Seika Kaisha, Japan |
| Year first mentioned: | 1995 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/273351054 |
| Citation: |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.