Compound ID | 435

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Ro 25-6833

Class: Beta-lactam

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Cell wall synthesis inhibitor
Description: (Lactamylvinyl)cephalosporin-type; Wuest J. In vitro activity of the novel Cephalosporins Ro 25-6833 and Ro 25-7031 against anaerobic bacteria. 35th-Intersci-Conf-Antimicrobial-Agents-Chemother 1995; 122
Institute where first reported: Hoffmann-La Roche Inc, Switzerland
Year first mentioned: 1995
Development status: Experimental
Chemical structure(s):
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Molecular weight: 546.5
Iso. SMILES: C1CN(C(=O)C1=CC2=C(N3[C@@H]([C@@H](C3=O)NC(=O)/C(=N\O)/C4=CSC(=N4)N)SC2)C(=O)O)CC(F)(F)F
InChI Key: NOAJGZYUGGBORE-RPACBQLBSA-N
Can. SMILES: C1CN(CC(F)(F)F)C(=O)C1=CC2=C(C(=O)O)N3C(=O)[C@H]([C@H]3SC2)NC(=O)/C(=N\O)/C4=CSC(=N4)N
InChI: InChI=1S/C19H17F3N6O6S2/c20-19(21,22)6-27-2-1-7(14(27)30)3-8-4-35-16-11(15(31)28(16)12(8)17(32)33)25-13(29)10(26-34)9-5-36-18(23)24-9/h3,5,11,16,34H,1-2,4,6H2,(H2,23,24)(H,25,29)(H,32,33)/b7-3?,26-10-/t11-,16-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9578062
Citation: https://doi.org/10.1021/js970261f

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