Compound ID | 440
TOC-50
Class: Beta-lactam (cephalosporin)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Potent against both MSSA and MRSA. Able to outcompete penicillinG in binding to PBP from MRSA. |
| Description: | Hanaki H, Akagi H, Shimizu C, et al., Active new Cephalosporin, TOC-39, TOC-50, against multi-resistant MRSA. 33rd-Intersci-Conf-Antimicrobial-Agents-Chemother 1993; 282. |
| Institute where first reported: | Taiho Pharmaceuticals, Japan and Otsuka Chemical Co., Japan |
| Year first mentioned: | 1993 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/274913048 |
| Citation: |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.