Compound ID | 448
Synonym(s): S-1090
Class: Beta-lactam (cephalosporin)
Spectrum of activity: | Gram-positive & Gram-negative |
Details of activity: | Broad spectrum antibiotic taken to phase III clinical trials but failed to be registered. It was active against Steptococcus pyogenes, S. pneumoniae, H. influenzae and many other species. |
Description: | Tsuji M, Ishii Y, Ohno A, et al. In vitro and in vivo antibacterial activities of S-1090, a new oral Cephalosporin. Antimicrobial Agents and Chemotherapy. 1995;39(11):2544. |
Institute where first reported: | Shionogi, Japan |
Year first mentioned: | 1992 |
Highest developmental phase: | Phase 3 |
Development status: | Inactive |
Chemical structure(s): | |||||||||||
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External links: | |
PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/6400678 |
Guide to Pharmacology: | cefmatilen |
Citation: | https://journals.asm.org/doi/10.1128/aac.39.11.2544?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed |