Compound ID | 454
Class: Cephalosporin-triclosan
Spectrum of activity: | Gram-negative |
Details of activity: | Improved in vivo activity compared with NB2030 but also have reduced in vitro antibacterial activity |
Description: | Li Q, Doppalapudi VR, Castillo R, et al. Analogs of NB2030, a Cephalosporin-triclosan conjugate, with reduced serum protein binding capacity. 43rd-ICAAC 2003;268 |
Institute where first reported: | New Biotics (Kiadis Pharmaceuticals, Netherlands) |
Year first mentioned: | 2003 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
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