Compound ID | 469
NB3322
Class: Dihydrofolate reductase inhibitor
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Inhibits folate biosynthesis; bacteriocidal activity against MRSA, VRE, M. catarrrhalis, H. influenzae and S. pneumoniae |
| Description: | Li Q, Bueno A, Lee JY, et al. NB3322, a DHFR inhibitor with antibacterial activity in vitro and in vivo. 43rd-ICAAC 2003;272 |
| Institute where first reported: | New Biotics (Kiadis Pharmaceuticals, Netherlands) |
| Year first mentioned: | 2003 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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