Compound ID | 474
Ro-626091
Class: Small molecule antibacterial agent
| Agent Type: | Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Folate synthesis inhibitor. Dihydrofolate reductase inhibitor |
| Target Pathogen: | Active against trimethoprim-resistant Staphylococcus aureus |
| Description: | Trimethoprim derivative |
| Institute where first reported: | Hoffmann-La Roche Inc, Switzerland |
| Year first mentioned: | 1999 |
| Development status: | Experimental |
| External links: |
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