Compound ID | 483

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PGE-9509924

Class: Quinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: DNA gyrase inhibitors; DNA topoisomerase inhibitors; active against atypical respiratory tract infection
Institute where first reported: Procter and Gamble Pharmaceuticals, US
Year first mentioned: 2000
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 357.4
Iso. SMILES: COC1=C(C=CC2=C1N(C=C(C(=O)O)C2=O)C3CC3)N4CCC[C@H](N)C4
InChI Key: ZASYVQUJFRKPOO-NSHDSACASA-N
Can. SMILES: COC1=C2C(=CC=C1N3CCC[C@@H](C3)N)C(=O)C(=CN2C4CC4)C(=O)O
InChI: InChI=1S/C19H23N3O4/c1-26-18-15(21-8-2-3-11(20)9-21)7-6-13-16(18)22(12-4-5-12)10-14(17(13)23)19(24)25/h6-7,10-12H,2-5,8-9,20H2,1H3,(H,24,25)/t11-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/substance/273122357
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC127266/
  • https://pubchem.ncbi.nlm.nih.gov/substance/273122357

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