Compound ID | 49

SASPject4

Class: Bacteriophage and/or bacteriophage-derived product

Agent Type: Bacteriophage or bacteriphage-derived product;
Spectrum of activity: Gram-negative
Mechanism of action: Utilises small acid soluble spore proteins which bind to DNA
Target Pathogen: Active against Escherichia coli an d Klebsiella pneumoniae
Propensity to select resistant mutants: Yes
Description: Developed for systemic/intravenous application; delivered by bacteriophage
Institute where first reported: Phico Therapeutics Ltd., UK
Year first mentioned: 2014
Highest developmental phase: Preclinical
Development status: Experimental

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