Compound ID | 495

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MF 961

Synonym(s): MF-961  |  MF961

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive
Mechanism of action: DNA synthesis inhibitor
Propensity to select resistant mutants: A comparison against ofloxacin, fleroxacin and rufloxacin yielded the least resistant mutants
Description: Rufloxacin derivative
Institute where first reported: University of Birmingham, UK
Year first mentioned: 1989
Development status: Experimental
Chemical structure(s):
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Molecular weight: 395.43
Iso. SMILES: CN1CCN(CC1)C2=C(C=C3C4=C2SCC(N4C=C(C3=O)C(=O)O)CF)F
InChI Key: YHMYZZSLDKKBQL-UHFFFAOYSA-N
Can. SMILES: CN1CCN(CC1)C2=C3C4=C(C=C2F)C(=O)C(=CN4C(CF)CS3)C(=O)O
InChI: InChI=1S/C18H19F2N3O3S/c1-21-2-4-22(5-3-21)15-13(20)6-11-14-17(15)27-9-10(7-19)23(14)8-12(16(11)24)18(25)26/h6,8,10H,2-5,7,9H2,1H3,(H,25,26)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/124046
Citation: https://doi.org/10.1093/jac/29.6.649

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