Compound ID | 497
Synonym(s): RP-67829 | RP67829
Class: DNA synthesis inhibitor
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | DNA synthesis inhibitor. Bacterial topoisomerase inhibitor |
| Target Pathogen: | Active against staphylococci, streptococci (including Streptococcus pneumoniae), Neisseria spp., Moraxella catarrhalis, and Haemophilus influenzae |
| Description: | A benzonaphthyridine antibiotic |
| Institute where first reported: | Rhone-Poulenc Rorer, France |
| Year first mentioned: | 1991 |
| Development status: | Experimental |
| External links: | |
| Citation: | http://jac.oxfordjournals.org/content/31/2/273.long |