Compound ID | 499
QX-5-2987
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | DNA synthesis inhibitor. Reported as ParE inhibitor |
| Target Pathogen: | Active against Enterococcus faecalis, methicillin-resistant and quinolone-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and Streptococcus pneumoniae |
| Institute where first reported: | Quorex pharmaceuticals, USA |
| Year first mentioned: | 2004 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://pubs.acs.org/doi/10.1021/id500013t |
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