Compound ID | 519

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Fosmidomycin

Synonym(s): FR 31564

Class: Natural product antibiotic

Agent Type: Natural product;
Spectrum of activity: Gram-negative
Mechanism of action: Isoprenoid synthesis inhibitor
Target Pathogen: Active against Pseudomonas aeruginosa and Salmonella typhi
Institute where first reported: Fujisawa Pharmaceutical Co., Ltd. (Japan)
Year first mentioned: 1980
Development status: Experimental
Chemical structure(s):
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Molecular weight: 183.1
Iso. SMILES: C(CN(C=O)O)CP(=O)(O)O
InChI Key: GJXWDTUCERCKIX-UHFFFAOYSA-N
Can. SMILES: C(CN(C=O)O)CP(=O)(O)O
InChI: InChI=1S/C4H10NO5P/c6-4-5(7)2-1-3-11(8,9)10/h4,7H,1-3H2,(H2,8,9,10)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/572
Guide to Pharmacology: fosmidomycin
Citations:
  • https://www.sciencedirect.com/science/article/pii/S0040403998017559
  • https://www.jstage.jst.go.jp/article/antibiotics1968/33/1/33_1_24/_article

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