Compound ID | 532
Synonym(s): Riburamycin | RU-75411 | RU 75411
Class: Small molecule antibacterial agent
| Agent Type: | Semisynthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor. MraY inhibitor; interferes with cell-wall synthesis by inhibiting transfer of the peptidoglycan precursor moiety (MurNAc-pentapeptide) to the membrane lipid carrier, undecaprenyl phosphate |
| Description: | A liposidomycin analogue |
| Institute where first reported: | Aventis (Sanofi-Aventis, France) |
| Year first mentioned: | 2002 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| External links: | |
| Structure link: | See source publication |
| Citation: | https://doi.org/10.1111/j.1469-0691.2005.01141.x |