Compound ID | 535
CG-400463
Class: Fatty acid synthesis inhibitor (FabI inhibitor, naphthylidine derivative)
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Inhibits FabI, which determins the completing of each cycle of elongation in the fatty acid synthesis. |
| Description: | Kim C, Lee C, Kim J, Kang S, et al. CG400462 and CG400463, a novel FabI inhibitor with potent in vivo activity. 46th-Intersci-Conf-Antimicrobial-Agents-Chemother 2006;210 |
| Institute where first reported: | Crystal Genomics, Republic of Korea |
| Year first mentioned: | 2006 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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