Compound ID | 536
JNJ-17156581
Class: Macrolide
| Agent Type: | Semisynthetic; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Protein synthesis inhibitor |
| Target Pathogen: | Active against Gram-positive cocci and Haemophilus influenzae |
| Description: | A 2-fluoro-6-O-3-(biheteroaryl)-2-propenyl ketolide derived from 15-methylerythromycin A; Abbanat DR, Ashley G, Foleno B, FU H, Hilliard J, et al. In vitro and in vivo antibacterial activities of 15-methyl-2-fluoro ketolides. 43rd-ICAAC 2003;246 |
| Institute where first reported: | Kosan Biosciences, USA; Johnson & Johnson Pharmaceutical, US A |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://doi.org/10.1093/jac/dkh169 |
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