Compound ID | 548

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PD 138312

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Description: Shapiro MA, Dever JA, Joannides ET and Sesnie JC, et al. In vivo activity of PD-138312, a new F-naphthyridine with excellent Gram-positive potency. 33rd-Intersci-Conf-Antimicrobial-Agents-Chemother 1993; 306.
Institute where first reported: Pfizer, USA
Year first mentioned: 1993
Development status: Experimental
Chemical structure(s):
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Molecular weight: 374.41
Iso. SMILES: CC(C)(C1CCN(C1)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F)N
InChI Key: WZGKUGHHTACDTE-UHFFFAOYSA-N
Can. SMILES: CC(C)(C1CCN(C1)C2=NC3=C(C=C2F)C(=O)C(=CN3C4CC4)C(=O)O)N
InChI: InChI=1S/C19H23FN4O3/c1-19(2,21)10-5-6-23(8-10)17-14(20)7-12-15(25)13(18(26)27)9-24(11-3-4-11)16(12)22-17/h7,9-11H,3-6,8,21H2,1-2H3,(H,26,27)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/129536
Citations:
  • http://aac.asm.org/content/38/2/369.short
  • https://doi.org/10.1128/aac.37.12.2563

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