Compound ID | 550

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Premafloxacin (U95376)

Class: Fluoroquinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Was in development for veterinary medicine and is potent against both Gram positive and negative
Institute where first reported: The Upjohn Company (Pfizer, USA)
Year first mentioned: 1995
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 403.45
Iso. SMILES: C[C@@H]([C@@H]1CCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F)NC
InChI Key: SUQUWONDIBHQOZ-NWDGAFQWSA-N
Can. SMILES: C[C@@H]([C@@H]1CCN(C1)C2=C(C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(=O)O)OC)NC
InChI: InChI=1S/C21H26FN3O4/c1-11(23-2)12-6-7-24(9-12)18-16(22)8-14-17(20(18)29-3)25(13-4-5-13)10-15(19(14)26)21(27)28/h8,10-13,23H,4-7,9H2,1-3H3,(H,27,28)/t11-,12+/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/71455
Guide to Pharmacology: premafloxacin
Citations:
  • http://jac.oxfordjournals.org/content/38/4/742.full.pdf
  • https://www.sciencedirect.com/science/article/pii/S0022354915504449?via%3Dihub

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