Compound ID | 557

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PD 163049

Class: Fluoroquinolone

Spectrum of activity: Gram-positive
Details of activity: Active against a number of species of Mycobacteria including M. tuberculosis, M. fortuitum and M. smegmatis
Description: Renau TE, Gage JW, Dever JA, et al. Antituberculosis activity and side effect profiles of 8 new quinolones optimised for antimycobacterial effects. 36th-Intersci-Conf-Antimicrobial-Agents-Chemother 1996; 136.
Institute where first reported: Parke Davis Pharmaceutical Research (Pfizer, USA)
Year first mentioned: 1996
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 376.43
Iso. SMILES: C[C@@H]1CN(C[C@@H](N1)C)C2=C(C=C3C(=O)C(=CN(C3=N2)C(C)(C)C)C(=O)O)F
InChI Key: OEDVZYKCNVQWEL-PHIMTYICSA-N
Can. SMILES: C[C@H]1CN(C[C@@H](C)N1)C2=NC3=C(C=C2F)C(=O)C(=CN3C(C)(C)C)C(=O)O
InChI: InChI=1S/C19H25FN4O3/c1-10-7-23(8-11(2)21-10)17-14(20)6-12-15(25)13(18(26)27)9-24(16(12)22-17)19(3,4)5/h6,9-11,21H,7-8H2,1-5H3,(H,26,27)/t10-,11+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/459971
Citation: https://journals.asm.org/doi/10.1128/aac.40.10.2363

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