Cetefloxacin

Class: Fluoroquinolone

Spectrum of activity:	Gram-positive  &  Gram-negative
Details of activity:	Activity is similar to temafloxacin against the tested K. pneumoniae, P. stuartii, MSSA, Enterococci and S. pyogenes.
Description:	Jones RN, Barrett MS and Erwin ME. In vitro antimicrobial evaluations of a new fluoroquinolone, E-4868 (E-4). 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 238.
Institute where first reported:	Esteve, Spain
Year first mentioned:	1992
Highest developmental phase:	Phase 1
Development status:	Inactive

Chemical structure(s):
Canonical SMILES:	C[C@H]1[C@@H](CN1C2=CC3=C(C=C2F)C(=O)C(=CN3C4=CC=C(C=C4F)F)C(=O)O)N
Isomeric SMILES:	C[C@H]1[C@@H](CN1C2=C(C=C3C(=C2)N(C=C(C3=O)C(=O)O)C4=C(C=C(C=C4)F)F)F)N
InChI:	InChI=1S/C20H16F3N3O3/c1-9-15(24)8-25(9)18-6-17-11(5-14(18)23)19(27)12(20(28)29)7-26(17)16-3-2-10(21)4-13(16)22/h2-7,9,15H,8,24H2,1H3,(H,28,29)/t9-,15+/m0/s1
InChI Key:	LTDOHCZUKCZDEQ-BJOHPYRUSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/65995

External links:
Guide to Pharmacology:	cetefloxacin
Main Source:	https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0031-1300058