Compound ID | 574

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PGE 4175997

Class: Quinolone

Spectrum of activity: Gram-positive  &  Gram-negative
Institute where first reported: Procter and Gamble Pharmaceuticals
Year first mentioned: 1999
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: Procter and Gamble Pharmaceuticals seems to have withdrawn from antibiotic R&D
Chemical structure(s):
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Molecular weight: 385.46
Iso. SMILES: COC1=C(C=CC2=C1N(C=C(C(=O)O)C2=O)C3CC3)N4CC[C@H](C4)C(C)(C)N
InChI Key: OKLKAFJDLMXNMT-GFCCVEGCSA-N
Can. SMILES: CC(C)([C@@H]1CCN(C1)C2=CC=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)N
InChI: InChI=1S/C21H27N3O4/c1-21(2,22)12-8-9-23(10-12)16-7-6-14-17(19(16)28-3)24(13-4-5-13)11-15(18(14)25)20(26)27/h6-7,11-13H,4-5,8-10,22H2,1-3H3,(H,26,27)/t12-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/substance/273122356
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC90847/
  • https://journals.asm.org/doi/10.1128/aac.45.12.3422-3426.2001

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