Compound ID | 576

Update compound information

A-170568

Class: Fluoroquinolone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: DNA synthesis inhibitor. Bacterial topoisomerase inhibitor
Description: Nilius AM, Hensy-Rudloff DM, Almer LS, et al. Comparative in vitro antibacterial activity of A-170568.1, a novel 2-pyridone antibacterial agent. 38th-Intersci-Conf-Antimicrobial-Agents-Chemother 1998; 252.
Institute where first reported: Abbott Laboratories, USA
Year first mentioned: 1998
Development status: Experimental
Chemical structure(s):
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Molecular weight: 385.43
Iso. SMILES: CC1=C(C(=CN2C1=C(C=C(C2=O)C(=O)O)C3CC3)F)N4C[C@H](C5(C4)CC5)NC
InChI Key: RAPWMGPTVTUAQY-MRXNPFEDSA-N
Can. SMILES: CC1=C(C(=CN2C1=C(C=C(C2=O)C(=O)O)C3CC3)F)N4C[C@H](C5(CC5)C4)NC
InChI: InChI=1S/C21H24FN3O3/c1-11-17-13(12-3-4-12)7-14(20(27)28)19(26)25(17)8-15(22)18(11)24-9-16(23-2)21(10-24)5-6-21/h7-8,12,16,23H,3-6,9-10H2,1-2H3,(H,27,28)/t16-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/486121
Citation: https://doi.org/10.1086/317490

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