Compound ID | 584
Walkmycin F
Class: Histidine kinase inhibitor
| Spectrum of activity: | Gram-negative |
| Details of activity: | Inhibits the two component system WalK/ WalR, which is essentual for cell wall metabolism in Bacillus subtilis and S. aureus. The MICs for Walkamycin F is 64 µg/ml |
| Description: | Igarashi M, Eguchi Y, Umekita M, et al. Walkmycins, the Novel Histidine Kinase Inhibitors. 50th-ICAAC 2010 |
| Institute where first reported: | Inst. of Microbial Chemistry, Japan, Kinki Univ. Sch. of Agriculture, Japan. |
| Year first mentioned: | 2010 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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