Compound ID | 585

PGE 1818689

Class: Beta-lactam; quinolone

Agent Type: Semisynthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Cell wall synthesis inhibitor. Additionally DNA synthesis inhibitor ; Gyrase inhibitor
Target Pathogen: Active against Escherichia coli and Staphylococcus aureus
Description: Mallalieu NI, Bierman JC, Dorsey JS, et al. Pharmacokinetics and in vivo efficacy of quinolonyl-carbacephem antibacterials in animals. 38th-Intersci-Conf-Antimicrobial-Agents-Chemother 1998; 281.
Institute where first reported: Procter Gamble Pharmaceuticals, Ireland
Year first mentioned: 1998
Highest development stage: Preclinical
Development status: Experimental
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