Compound ID | 590
RWJ-49815
Class: Antivirulence agent
| Agent Type: | Synthetic; Small molecule; Direct acting; Antivirulence; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Antivirulence agent; two-component system inhibitor |
| Target Pathogen: | Active against multidrug-resistant Staphylococcus aureus and Enterococcus faecium |
| Description: | Demers JP, Bernstein JJ, Fernandez JA, et al. The identification of RWJ-49815, a novel inhibitor of bacterial two-component regulatory systems and a potent Gram positive antibacterial. 37th-Intersci-Conf-Antimicrobial-Agents-Chemother 1997; 185. |
| Institute where first reported: | Johnson & Johnson Pharmaceutical R&D, USA |
| Year first mentioned: | 1997 |
| Development status: | Experimental |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/516731 |
| Citation: | https://doi.org/10.1073/pnas.95.9.5317 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.