Compound ID | 590

RWJ-49815

Class: Antivirulence agent (two-component system inhibitor)

Spectrum of activity: Gram-positive
Details of activity: Potent activity against multidrug resistant S. aureus and E. faecium
Description: Demers JP, Bernstein JJ, Fernandez JA, et al. The identification of RWJ-49815, a novel inhibitor of bacterial two-component regulatory systems and a potent Gram positive antibacterial. 37th-Intersci-Conf-Antimicrobial-Agents-Chemother 1997; 185.
Institute where first reported: Johnson & Johnson Pharmaceutical R&D, USA
Year first mentioned: 1997
Highest developmental phase: Preclinical
Development status: Inactive
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/516731
Citation:

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