Compound ID | 590
Class: Antivirulence agent (two-component system inhibitor)
Spectrum of activity: | Gram-positive |
Details of activity: | Potent activity against multidrug resistant S. aureus and E. faecium |
Description: | Demers JP, Bernstein JJ, Fernandez JA, et al. The identification of RWJ-49815, a novel inhibitor of bacterial two-component regulatory systems and a potent Gram positive antibacterial. 37th-Intersci-Conf-Antimicrobial-Agents-Chemother 1997; 185. |
Institute where first reported: | Johnson & Johnson Pharmaceutical R&D, USA |
Year first mentioned: | 1997 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
External links: | |
PubChem link: | https://pubchem.ncbi.nlm.nih.gov/compound/516731 |
Citation: |