Compound ID | 595
CHIR 380
Class: Macrolide
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against macrolide-resistant and -sensitive stains of Streptococcus pneumoniae and Streptococcus pyogenes |
| Description: | Compared to telithromycin demonstrates a greater lung to plasma distribution and half life making a good candidate for treatment of respiratory infections; Chu D, Barker L, Shawar R, et al. CHIR 380 and CHIR 988: Two novel potent ketolides. 43rd-ICAAC-2003 2003;245. |
| Institute where first reported: | Chiron Corp. (Novartis, Switzerland) |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
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