Compound ID | 599
API7444
Class: Antimicrobial peptide (lantibiotic)
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae |
| Description: | Toriya M, Shizmu, K, Ishiguro M, et al. In vitro and in vivo antimicrobial activity of a novel lantibiotic- AP17444. 44th-ICAAC 2004; 232. |
| Institute where first reported: | Asahikasei Pharma. Corp., Japan |
| Year first mentioned: | 2004 |
| Development status: | Experimental |
| Reason dropped: | In mouse models, activity against MRSA was weaker than currently used treatments |
| External links: |
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