Compound ID | 617

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YM17K (MC 352)

Class: Macrolide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Lower MICs than arithromycin against isolates of S. aureus, S. pyogenes, H. influenzae, E. faecalis, P. aeruginosa and N. gonorrhoeae but not E. coli.
Description: Kikuchi Y, Kojima N, Ikeda C, et al. Pharmacokinetics of YM17K, a new 16-membered macrolide in mce, rabbits and dogs. 33rd-Intersci-Conf-Antimicrobial-Agents-Chemother 1993; 197.
Institute where first reported: Yamanouchi, Japan
Year first mentioned: 1993
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
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Molecular weight: 565.74
Iso. SMILES: CCC1C(C=C(C=CC(=O)C(CC(C(C(CCC(=O)O1)C)OC2C(C(CC(O2)C)N(C)C)O)CC=O)C)C)CO
InChI Key: IBYMOKAONAMZRG-UHFFFAOYSA-N
Can. SMILES: CCC1C(C=C(C)C=CC(=O)C(C)CC(CC=O)C(C(C)CCC(=O)O1)OC2C(C(CC(C)O2)N(C)C)O)CO
InChI: InChI=1S/C31H51NO8/c1-8-27-24(18-34)15-19(2)9-11-26(35)21(4)16-23(13-14-33)30(20(3)10-12-28(36)39-27)40-31-29(37)25(32(6)7)17-22(5)38-31/h9,11,14-15,20-25,27,29-31,34,37H,8,10,12-13,16-18H2,1-7H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/53423433
Citation:

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