Compound ID | 620
EP-014887
Class: Macrolide
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Protein synthesis inhibitor. Binds to the peptidyl transferase site of the 50S subunit of ribosomes |
| Description: | Tang D, Polemeropoulos A, Jiang L, et al. Discovery of EP-014887: a novel oxime 3,6-bicyclolide with high potency against MRSA and a favorable in vivo efficacy profile. 47th-ICAAC-2007 2007;246-247 |
| Institute where first reported: | Enanta Pharmaceuticals, USA |
| Year first mentioned: | 2007 |
| Development status: | Experimental |
| External links: | |
| Structure link: | https://www.sciencedirect.com/science/article/abs/pii/S0960894X08009049?via%3Dihub |
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