Compound ID | 624

Update compound information

CE-156811

Agent Type: Semisynthetic; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Protein synthesis inhibitor. Inhibits bacterial ribosomal peptidyl transferase
Target Pathogen: Active against methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and penicillin-resistant Streptococcus pneumoniae
Institute where first reported: Pfizer, USA
Year first mentioned: 2006
Development status: Experimental
Chemical structure(s):
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Molecular weight: 473.44
Iso. SMILES: C/C(=C\C1=CC(=C(C=C1F)OC[C@@H](C2CC2)F)F)/C(=O)N[C@H]3[C@H]([C@@H]([C@H]4[C@@H]([C@H]3O)OCO4)O)O
InChI Key: SIOAQNNLFVHYDC-KURXJLPMSA-N
Can. SMILES: C/C(=C\C1=C(C=C(C(=C1)F)OC[C@@H](C2CC2)F)F)/C(=O)N[C@H]3[C@H]([C@@H]([C@H]4[C@@H]([C@H]3O)OCO4)O)O
InChI: InChI=1S/C22H26F3NO7/c1-9(22(30)26-16-17(27)19(29)21-20(18(16)28)32-8-33-21)4-11-5-13(24)15(6-12(11)23)31-7-14(25)10-2-3-10/h4-6,10,14,16-21,27-29H,2-3,7-8H2,1H3,(H,26,30)/b9-4+/t14-,16-,17+,18-,19-,20+,21-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/72941976
Citation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443909/

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