Compound ID | 624

Update compound information

CE-156811

Class: Hygromycin A

Spectrum of activity: Gram-positive
Details of activity: Inhibits bacterial ribosomal peptidyl transferase. Effective against MRSA, VRE and PRSP
Institute where first reported: Pfizer, USA
Year first mentioned: 2006
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
Click here for structure editor
Molecular weight: 473.44
Iso. SMILES: C/C(=C\C1=CC(=C(C=C1F)OC[C@@H](C2CC2)F)F)/C(=O)N[C@H]3[C@H]([C@@H]([C@H]4[C@@H]([C@H]3O)OCO4)O)O
InChI Key: SIOAQNNLFVHYDC-KURXJLPMSA-N
Can. SMILES: C/C(=C\C1=C(C=C(C(=C1)F)OC[C@@H](C2CC2)F)F)/C(=O)N[C@H]3[C@H]([C@@H]([C@H]4[C@@H]([C@H]3O)OCO4)O)O
InChI: InChI=1S/C22H26F3NO7/c1-9(22(30)26-16-17(27)19(29)21-20(18(16)28)32-8-33-21)4-11-5-13(24)15(6-12(11)23)31-7-14(25)10-2-3-10/h4-6,10,14,16-21,27-29H,2-3,7-8H2,1H3,(H,26,30)/b9-4+/t14-,16-,17+,18-,19-,20+,21-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/72941976
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2443909/

  • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.