Compound ID | 63

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GL13K

Class: Antimicrobial peptide

Agent Type: Semisynthetic; Direct acting;
Spectrum of activity: Gram-negative
Mechanism of action: Membrane-active agent
Target Pathogen: Active against Pseudomonas aeruginosa biofilm when combined with tobramycin
Combined with other compounds: Yes
Description: Semisynthetic compound derived from salivary protein parotid secretory protein (BPIFA2)
Institute where first reported: Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, Minneapolis, Minnesota, USA
Year first mentioned: 2011
Development status: Experimental
External links:
Citations:
  • http://aac.asm.org/content/57/10/4903.full
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3417823/
  • https://www.biorxiv.org/content/10.1101/2025.10.02.679978v1
  • https://www.sciencedirect.com/science/article/pii/S0005273613001806?via%3Dihub#bb0115

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