Compound ID | 639
Class: Peptidylnucleoside
Spectrum of activity: | Gram-negative |
Details of activity: | Anti-pseudomonal activity |
Description: | Ganguli BN, Nadarni SR, Patel MV, et al. Napsamycins new anti-pseudomonas antibiotics. 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 195 |
Year first mentioned: | 1992 |
Highest developmental phase: | Preclinical |
Development status: | Inactive |
Chemical structure(s): | |
Canonical SMILES: | CC(C(C(=O)N/C=C\1/CC(C(N2CCC(=O)NC2=O)O1)O)NC(=O)C(CCSC)NC(=O)NC(CC3=CC=CC(=C3)O)C(=O)O)N(C)C(=O)C4CC5=CC(=CC=C5CN4)O |
Isomeric SMILES: | CC(C(C(=O)N/C=C\1/CC(C(O1)N2CCC(=O)NC2=O)O)NC(=O)C(CCSC)NC(=O)NC(CC3=CC(=CC=C3)O)C(=O)O)N(C)C(=O)C4CC5=C(CN4)C=CC(=C5)O |
InChI: | InChI=1S/C39H50N8O12S/c1-20(46(2)35(54)28-16-23-15-25(49)8-7-22(23)18-40-28)32(34(53)41-19-26-17-30(50)36(59-26)47-11-9-31(51)44-39(47)58)45-33(52)27(10-12-60-3)42-38(57)43-29(37(55)56)14-21-5-4-6-24(48)13-21/h4-8,13,15,19-20,27-30,32,36,40,48-50H,9-12,14,16-18H2,1-3H3,(H,41,53)(H,45,52)(H,55,56)(H2,42,43,57)(H,44,51,58)/b26-19- |
InChI Key: | MFEPAAMYDYMBSN-XHPQRKPJSA-N |
Structure link: | https://pubchem.ncbi.nlm.nih.gov/compound/3037898 |
External links: | |
Guide to Pharmacology: | napsamycin C |
Main Source: | https://www.jstage.jst.go.jp/article/antibiotics1968/47/5/47_5_595/_article |