Napsamycin D

Class: Peptidylnucleoside

Spectrum of activity:	Gram-negative
Details of activity:	Anti-pseudomonal activity
Description:	Ganguli BN, Nadarni SR, Patel MV, et al. Napsamycins new anti-pseudomonas antibiotics. 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 195
Year first mentioned:	1992
Highest developmental phase:	Preclinical
Development status:	Inactive

Chemical structure(s):
Canonical SMILES:	CC1C2=CC=C(C=C2CC(C(=O)N(C)C(C)C(C(=O)N/C=C\3/CC(C(N4CCC(=O)NC4=O)O3)O)NC(=O)C(CCSC)NC(=O)NC(CC5=CC=CC(=C5)O)C(=O)O)N1)O
Isomeric SMILES:	CC1C2=C(CC(N1)C(=O)N(C)C(C)C(C(=O)N/C=C\3/CC(C(O3)N4CCC(=O)NC4=O)O)NC(=O)C(CCSC)NC(=O)NC(CC5=CC(=CC=C5)O)C(=O)O)C=C(C=C2)O
InChI:	InChI=1S/C40H52N8O12S/c1-20-27-9-8-25(50)16-23(27)17-29(42-20)36(55)47(3)21(2)33(35(54)41-19-26-18-31(51)37(60-26)48-12-10-32(52)45-40(48)59)46-34(53)28(11-13-61-4)43-39(58)44-30(38(56)57)15-22-6-5-7-24(49)14-22/h5-9,14,16,19-21,28-31,33,37,42,49-51H,10-13,15,17-18H2,1-4H3,(H,41,54)(H,46,53)(H,56,57)(H2,43,44,58)(H,45,52,59)/b26-19-
InChI Key:	AZGANZVUWUCOGH-XHPQRKPJSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/3037899

External links:
Guide to Pharmacology:	napsamycin D
Main Source:	https://www.jstage.jst.go.jp/article/antibiotics1968/47/5/47_5_595/_article