Compound ID | 657
MCB3130
Class: Oxazolidinone-quinolone
| Spectrum of activity: | Gram-negative |
| Details of activity: | The hybrid compound is MICs ≤0.25μg/ml of MSSA, MRSA, PRSP, VRE, linezolid reistant S. aureus and E. faecalis. It also retained activity against quinolone resistant bacteria with mutations in grA and/or parC. |
| Description: | Locher HH, Borer Y, Gaertner M, et al. Antibacterial characterisation and mode of action of new oxazolidinone-quinolone hybrids. 43rd-ICAAC 2003;269 |
| Institute where first reported: | Morphochem AG (Biovertis, Austria) |
| Year first mentioned: | 2003 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| Reason Dropped: | Morphochem AG was taken over in 2006 by Biovertis AG but continued research till 2006 when finances wre prioritised to advanced projects only. |
| External links: | |
| Citation: |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.