Compound ID | 657
MCB3130
Class: Oxazolidinone; quinolone
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | DNA synthesis inhibitor |
| Target Pathogen: |
Active against methicillin-resistant and -susceptible Staphylococcus aureus, penicillin-resistant |
| Description: | Retains activity against quinolone-resistant bacteria with mutations in GyrA and/or ParC; Locher HH, Borer Y, Gaertner M, et al. Antibacterial characterisation and mode of action of new oxazolidinone-quinolone hybrids. 43rd-ICAAC 2003;269 |
| Institute where first reported: | Morphochem AG (Biovertis, Austria) |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
| Reason dropped: | Morphochem AG was taken over in 2006 by Biovertis AG but continued research till 2006 when finances were prioritised to advanced projects only. |
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