Compound ID | 67
Streptomyces papain inhibitor [SPI]
Class: Antimicrobial peptide
| Agent Type: | Natural product; Indirect acting; Antivirulence; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Inhibits bacterial virulence factors cysteine protease papain, cysteine protease bromelain, and serine protease trypsin |
| Target Pathogen: | Active against Bacillus anthracis, Staphylococcus aureus, Pseudomonas aeruginosa, and Vibrio cholerae |
| Description: | A papain inhibitory protein |
| Institute where first reported: | Department of Chemical Engineering and Biotechnology, University of Applied Sciences of Darmstadt, Darmstadt, Germany |
| Year first mentioned: | 2011 |
| Development status: | Experimental |
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