Compound ID | 675
VRC3324
Synonym(s): VRC-3324 | VRC 3324
Class: Protein synthesis inhibitor
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Mechanism of action: | Protein synthesis inhibitor. Peptide deformylase inhibitor |
| Description: | An alkyl succinate hydroxamic acid |
| Institute where first reported: | Vernalis, UK; Novartis, Switzerland; Pfizer, US |
| Year first mentioned: | 2000 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| Reason dropped: | Shows toxicity and high frequency to select resistant mutants |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/273137021 |
| Citation: | https://doi.org/10.1128/aac.46.9.2752-2764.2002 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.