Compound ID | 680
FCE 24964 (Prodrug FCE 25199)
Class: Beta-lactam (penem)
| Spectrum of activity: | Gram-positive |
| Details of activity: | In the mice model a post antibiotic effect was note after 2.5-4hrs for gram positive infections and 1.5-2.5 hours for gram negative infections. The gram postive infetions were induced by S. aureus, S. epidermidis or S. pyogenes and Gram negative infections were induced by Klebsiella, E. coli or Enterobacter. |
| Description: | Jabes D, Rossi R and Della Bruna C. Postantibioitc effect of the oral penem FCE 25199 in vitro and in vivo by a new cage model in mice. 32nd-Intersci-Conf-Antimicrobial-Agents-Chemother 1992; 175 |
| Institute where first reported: | Pharmacia Corp. (Pfizer, USA) |
| Year first mentioned: | 1992 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/274175391 |
| Citations: |
|
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.