Compound ID | 686
RTA-3
Class: Antimicrobial peptide
| Spectrum of activity: | Gram-positive |
| Details of activity: | Shown to be potent against P.aeruginosa, Aceinetobacter baumanniiand Stenotrophomonas maltophilia including colistin resistant strains. Studies in mice showed tolerance up to 50 fold the effective dose |
| Description: | Hawrani A, Dempsey C, Caetano T, et al. In vivo efficicacy and toxicity of the novel antimicrobial peptide RTA-2. 47th-ICAAC-2007 2007;243 |
| Institute where first reported: | Univerisity of Cardiff and Univerisity of Bristol, UK |
| Year first mentioned: | 2007 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
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