Compound ID | 71

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PRF-119

Class: Bacteriophage lysin

Spectrum of activity: Gram-positive
Details of activity: Specifically active against MSSA and MRSA (methicillin-sensitive and resistant Staphylococcus aureus). Progenitor of HY-133
Propensity to select resistant mutants: Yes
Institute where first reported: Institute of Medical Microbiology - University Hospital Münster, Münster,Germany
Year first mentioned: 2011
Highest developmental phase: Preclinical
Development status: Experimental
External links:
Citations:
  • In Vitro Activity against Staphylococcus aureus of a Novel Antimicrobial Agent, PRF-119, a Recombinant Chimeric Bacteriophage Endolysin By: Idelevich, Evgeny A.; von Eiff, Christof; Friedrich, Alexander W.; et al.
  • https://journals.asm.org/doi/10.1128/aac.00217-11

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