Compound ID | 729

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Tolevamer

Class: Polymer

Spectrum of activity: Gram-negative
Details of activity: Diarrhoea caused by Clostridium difficile
Institute where first reported: Genzyme Corporation
Year first mentioned: 2000
Highest developmental phase: Phase 3
Development status: Inactive
Reason Dropped: In phase III trials it did not show non-inferiority to vancomycin which resulted in a 6% share drop in Genzyme Corporation
Chemical structure(s):
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Molecular weight: 228.31
Iso. SMILES: CCC(CC)C1=CC=C(C=C1)S(=O)(=O)O
InChI Key: LZNNAMNPSXBDOT-UHFFFAOYSA-N
Can. SMILES: CCC(CC)C1=CC=C(C=C1)S(=O)(=O)O
InChI: InChI=1S/C11H16O3S/c1-3-9(4-2)10-5-7-11(8-6-10)15(12,13)14/h5-9H,3-4H2,1-2H3,(H,12,13,14)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/58817179
Citation:

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