Compound ID | 736

Update compound information

PNU 176665

Synonym(s): PNU-176665  |  PNU176665

Class: Oxazolidinone

Agent Type: Synthetic; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Protein synthesis inhibitor. Binds to the 30s ribosomal subunit
Target Pathogen: Active against Haemophilus influenzae, Streptococcus pneumoniae, and Staphylococcus aureus
Institute where first reported: Pharmacia &Upjohn ; Pharmacia Corp.; Pfizer, USA
Year first mentioned: 1999
Highest development stage: Preclinical
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 336.34
Iso. SMILES: CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)C3=NN=CS3)F
InChI Key: BSCPNDKHDRLNFH-JTQLQIEISA-N
Can. SMILES: CC(=O)NC[C@H]1CN(C2=CC(=C(C=C2)C3=NN=CS3)F)C(=O)O1
InChI: InChI=1S/C14H13FN4O3S/c1-8(20)16-5-10-6-19(14(21)22-10)9-2-3-11(12(15)4-9)13-18-17-7-23-13/h2-4,7,10H,5-6H2,1H3,(H,16,20)/t10-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/10404743
Citation: https://doi.org/10.3978/j.issn.2072-1439.2012.10.10

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.