Compound ID | 74
PlyPy
Class: Bacteriophage and/or bacteriophage-derived product
| Agent Type: | Natural product; Direct acting; Bacteriophage or bacteriphage-derived product; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Cell wall synthesis inhibitor. D-Alanyl-L-alanine endopeptidase inhibitor |
| Target Pathogen: | Active against streptococcal bacteraemia |
| Description: | Produced by prophage from Streptococcus pyogenes |
| Institute where first reported: | Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York, New York, USA |
| Year first mentioned: | 2014 |
| Development status: | Experimental |
| External links: | |
| Citations: |
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