Compound ID | 751

Update compound information

CP 642959

Class: Macrolide (ketolide)

Spectrum of activity: Gram-negative
Institute where first reported: Pfizer, USA
Year first mentioned: 2001
Highest developmental phase: Preclinical
Development status: Inactive
Reason Dropped: In animals its activity was less than telithromycin
Chemical structure(s):
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Molecular weight: 856.06
Iso. SMILES: O=C1O[C@]2([C@H](N1NCC[C@@H](C)N3C=C(C4=CC=CN=C4)N=C3)[C@@H](C)/C(/[C@H](C)C[C@](OC)(C)[C@H](O[C@@H]5O[C@H](C)C[C@H](N(C)C)[C@H]5O)[C@@H](C)C([C@H](C(O[C@@H]2CC)=O)C)=O)=N/OC)C
InChI Key: VVYXHLPFHNASRU-BPUPZIBESA-N
Can. SMILES: CC[C@@H]1[C@]2(C)[C@@H]([C@@H](C)/C(=N/OC)/[C@H](C)C[C@](C)([C@@H]([C@@H](C)C(=O)[C@@H](C)C(=O)O1)O[C@H]3[C@@H]([C@H](C[C@@H](C)O3)N(C)C)O)OC)N(C(=O)O2)NCC[C@@H](C)N4C=C(C5=CN=CC=C5)N=C4
InChI: InChI=1S/C44H69N7O10/c1-14-34-44(9)38(51(42(55)61-44)47-19-17-26(3)50-23-32(46-24-50)31-16-15-18-45-22-31)28(5)35(48-57-13)25(2)21-43(8,56-12)39(29(6)36(52)30(7)40(54)59-34)60-41-37(53)33(49(10)11)20-27(4)58-41/h15-16,18,22-30,33-34,37-39,41,47,53H,14,17,19-21H2,1-13H3/b48-35+/t25-,26-,27-,28+,29+,30-,33+,34-,37-,38-,39-,41+,43-,44-/m1/s1
External links:
Citation: https://www.drugfuture.com/synth/syndata.aspx?ID=313033

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