Compound ID | 765

Update compound information

AM-3005

Class: Mutilin-quinolone hybrid

Spectrum of activity: Gram-negative
Details of activity: Inhibits protein synthesis and bacterial Type II topoisomerases. Active against MRSA. Spontaneous mutants were identified which showed a mutation in rplV gene which encodes the L22 ribosomal protein.
Institute where first reported: Kyorin Pharamaceutical Co., Ltd., Japan
Year first mentioned: 2008
Highest developmental phase: Preclinical
Development status: Inactive
External links:
Citations:
  • https://idsa.confex.com/idsa/2008/webprogram/Paper25474.html
  • https://journals.lww.com/ijab/fulltext/2013/03010/recent_advances_in_antibacterial_drugs.2.aspx

    • AntibioticDB is supported by GARDP.

    If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

    The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.