Compound ID | 770
EP 13159
Class: Macrolide (ketolide)
| Spectrum of activity: | Gram-negative |
| Details of activity: | Protein synthesis inhibitor; effective against macrolide resistant S. aureus with MLSB- and MRSA resistant phenotype. It is also active against VRE, Enterococcus faecalis and E. faecium (1) |
| Description: | Phan LT, Amsler K, Polemeropoulos A, et al. In vitro and in vivo evaluation of EP-13159: a novel fluoro ketolide active agaisnt MRSA and VRE and with exceptional activities against resistant streptococci. 43rd-ICAAC 2003;242 |
| Institute where first reported: | Enanta Pharmaceuticals, USA |
| Year first mentioned: | 2003 |
| Highest developmental phase: | Preclinical |
| Development status: | Inactive |
| External links: | |
| Citation: |
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