Compound ID | 779
CHIR 281
Class: Macrolide
| Agent Type: | Semisynthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Protein synthesis inhibitor |
| Target Pathogen: | Active against macrolide-resistant and -susceptible bacteria including strains expressing erm genes and mef (efflux) resistance genes |
| Description: | Lin X, Burger M, Chu D, et al. Syntheses and in vitro antibacterial activity of novel des/nor-methyl ketolides. 43rd-ICAAC 2003;245 |
| Institute where first reported: | Chiron Corp. (Novartis, Switzerland) |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://doi.org/10.1016/j.bmcl.2006.05.104 |
AntibioticDB is supported by GARDP.
If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions
The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.