Compound ID | 781

EP-13543

Synonym(s): EP13543  |  EP 13543

Class: Macrolide

Agent Type: Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Protein synthesis inhibitor
Target Pathogen: Active against pathogens causing respiratory tract infections including Haemophilus influenzae, methicillin-resistant Staphylococcus aureus infections, Streptococcus sp., and vancomycin-resistant Enterococcus
Description: A ketolide; Scorneaux B, Arya A, Polemeropoulos A, et al. In vitro and in vivo evaluation of EP-13543: a novel ketolide active against resistant pathogens and efficacious in a H. influenzae mice lung infection model. 43rd-ICAAC 2003;243
Institute where first reported: Enanta Pharmaceuticals, USA
Year first mentioned: 2003
Development status: Experimental
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