Compound ID | 781
Synonym(s): EP13543 | EP 13543
Class: Macrolide
| Agent Type: | Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Protein synthesis inhibitor |
| Target Pathogen: | Active against pathogens causing respiratory tract infections including Haemophilus influenzae, methicillin-resistant Staphylococcus aureus infections, Streptococcus sp., and vancomycin-resistant Enterococcus |
| Description: | A ketolide; Scorneaux B, Arya A, Polemeropoulos A, et al. In vitro and in vivo evaluation of EP-13543: a novel ketolide active against resistant pathogens and efficacious in a H. influenzae mice lung infection model. 43rd-ICAAC 2003;243 |
| Institute where first reported: | Enanta Pharmaceuticals, USA |
| Year first mentioned: | 2003 |
| Development status: | Experimental |
| External links: |